David Marcinek: Biologist
Muscle endurance can be improved, in older adults, without physical exercise, according to the results of a new clinical trial. Scientists in the US and Switzerland say their research suggests supplementation with a gut metabolite, known as urolithin A, may counteract age-associated muscle decline. This is significant as a potential intervention that could slow the onset of frailty in older pe ople, and prolong healthspan. The study, sponsored by the Swiss life science company, Amazentis (also sponsors of this podcast), was conduced at the University of Washington Medical Center and the Fred Hutchinson Cancer Research Center in Seattle. It was designed to test the hypothesis that long-term supplementation with Mitopure, a highly pure, synthetic form of urolithin A, would improve mitochondrial function and muscle performance in older adults. In this Live Long and Master Aging (LLAMA) podcast interview, the study's principal investigator, Prof. David Marcinek, explains the
