There has been a lot of buzz recently surrounding a new supplement that could boost our energy levels as we grow old. It is a recently discovered form of vitamin B3 and has been widely touted as a possible tool to enhance the aging process. We are going to take a deep dive into what it is and how it works. Nicotinamide riboside (NR) is converted by the body into nicotinamide adenine dinucleotide (NAD) which is an essential molecule found in every living cell and plays a significant role in energy production, regulation of the circadian rhythm and cognitive function. Dr. Charles Brenner is one of the world’s leading authorities on the biochemistry behind NR and its potential to extend life in some organisms. Dr. Brenner is the Roy J. Carver Chair and Head of Biochemistry at the University of Iowa and founding co-director of the University of Iowa Obesity Initiative. He is also chief scientific adviser to Chromadex, a California-based company behind the NR supplement, Tru Niagen. In this in-depth interview, Dr Brenner explains the significance of NAD and why he believes supplementation with NR could help us “age better.” He also elaborates on why he refuses to describe NR as “miraculous or magic” and explains why he is uncomfortable with the often-heard expression, ‘anti-aging,’ in the marketing of human longevity.